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Active PROJECT GRANT Swedish Research Council

The future of cardiovascular diagnostics using exercise magnetic resonance imaging

40M kr SEK

Funder Swedish Research Council
Recipient Organization Lund University
Country Sweden
Start Date Jan 01, 2025
End Date Dec 31, 2028
Duration 1,460 days
Number of Grantees 1
Roles Principal Investigator
Data Source Swedish Research Council
Grant ID 2024-05439_VR
Grant Description

What will be done?

I will invent new magnetic resonance imaging (MRI) methods for quantification of cardiovascular flow and function during physical exercise, and apply the methods to understand  the super-normal function of the hearts of elite athletes, and to provide new insights into why patients with congenital heart disease have limited exercise tolerance.How will it be done?

I will use artificial intelligence and machine learning techniques to develop new three-dimensional and time-resolved (4D) motion-compensated MRI methods with images available within minutes after the patient scan.

Patient studies will be performed in close collaboration with world-leading clinical collaborators.Why is it important?The first signs of failure of the cardiovascular system are seen during physical exercise, and thus exercise imaging will provide novel information for early detection of disease, monitoring of disease progression, and surgical decision support.

However, current methods are too complex for clinical application and research studies, and are therefore barely used, and therefore the new methods will provide a quantum leap in cardiovascular diagnostics.Why me?

I have 15-years of experience of successful development of MRI methods for quantification of pathophysiology in the cardiovascular system.

Furthermore, I have excellent collaborations with clinical experts in the world-leading Cardiac MR Group in Lund, which ensures rapid translation of the results to clinical practice.

All Grantees

Lund University

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