HEADLINE - HEAlth Diagnostic eLectronIc NoSe

The project aims to design a hybrid electronic nose (e-Nose) for non-invasive diagnostic and health monitoring. Metabolic activity produces  volatile organic compounds (VOCs), that are excreted through, e.g., breath, blood, urine.

The types of VOCs and their relative concentrations are characteristic of specific disease processes and can be exploited for diagnostic purposes.

The aim is to create a hybrid e-Nose combining different sensor technologies and novel sensing materials, trained with specific AI models to selectively detect VOCs.HEADLINE is an international team with researchers from two universities in the US, one university and one company from Sweden aiming to design a hybrid e-Nose using advanced sensing materials and devices to be integrated in the form of a breathalyzer.

This can be used as a point-of-care portable device or a microanalysis platform to assist doctors in their diagnoses and in health monitoring.

HEADLINE works towards a cost-effective, versatile, and reliable diagnostic tool to promote proactive healthcare.The team has expertise in differing sensing technologies, AI/ML, and development of diagnostic tests.

Phase I of this NSF Convergence Accelerator Track L project focuses on designing sensor hardware and investigating AI models for the e-Nose system.

In Phase II, convergence activities will be expanded, involving multi-organization partnerships to conduct medical trials, gather end-user insights, and establish pathways for commercialization.