PREDEM: precision diagnostics and treatment och cognitive disorders and prevention of dementia

Purpose and goal:

Alzheimer´s disease and other dementias are among the biggest societal challenges of the coming decades. The innovation milieu PREDEM aims to prevent dementia disorders by developing and introducing new methods for early detection and investigation, accurate diagnostics and individualized prevention and treatment. The vision for PREDEM is that all people who are at risk of developing dementia are offered the best available preventive measures and treatments based on their individual circumstances.

Expected results and effects:

New tools and work procedures can lead to earlier detection of incipient dementia, faster and safer diagnostics, as well as better accessibility and adaptation of investigation methods to different patient groups. More accurate forecasting models can facilitate that the right efforts for prevention and treatment are implemented at the right time, and that the resources of healthcare and society are thus used in the best possible way. In the longer term, these measures are expected to lead to fewer people developing dementia.

Approach and implementation:

In the innovation milieu, we introduce digital tools and working methods for early detection and investigation of cognitive impairment. Moreover, we develop, validate and introduce new classes of biomarkers for precision diagnostics. We develop prediction models and decision support for individualized prevention and treatment and develop methods for evaluating cost-effectiveness of new diagnostic and treatment strategies as well as new payment models to ensure fast and equal access to cost-effective treatment.