PRIO Testbed for molecular phenotype level precision medicine

Purpose and goal:

Despite the great value of genomics in drug development, the recent, rather disappointing data from studies using genome-based treatment prediction clearly demonstrate that we need more information on the protein and cellular level to be able to match the right patient with the right drug at the right time. The goal of the PRIO testbed is to create a sustainable environment that speeds up the clinical implementation of next generation technologies for precision medicine in Sweden.

Expected results and effects:

Our goal is to form a sustainable environment for the academia and industry to enable the continuous introduction of new techniques and data types to guide clinical decision making. A sustainable hospital unit allows the introduction of emerging technologies to multi-omics studies, without a need for creating new sample and data workflows for each study. PRIO will further allow prospective trial-based technology testing and the collection of fresh material in parallel with routine biobanking.

Approach and implementation:

The existing hospital unit will be connected with KI/SciLifeLab by establishing a new physical sample preparation unit. The PRIO testbed will consist of experts running benchmark projects for the testbed, as well as business development and legal support to ensure growth and sustainability. In year two, the technology test-lab at the hospital will be connected to a physical environment where the Biotech, Pharma and MedTech industries can test their products and services in development.