National Genomic Infrastructure

The National Genomics Infrastructure (NGI) is an internationally leading infrastructure in genomics and a unique and exceptionally important resource for the Swedish research community.

NGI has more than 20-years of experience in providing large-scale genotyping and DNA sequencing as a collaborative service.

Significant efforts are made at NGI to evaluate emerging technologies and develop novel methods in the rapidly changing field of genomics.

This allows NGI to offer a unique combination of extensive consultative support (planning and project design meetings) and executive support (sequencing/ genotyping and pipeline analysis) for high-throughput DNA sequencing and genotyping to academic and industrial users in Sweden. Similar comprehensive services are not available from commercial suppliers or non-commercial genome centers.

The NGI facilities are hosted by Science for Life Laboratory (SciLifeLab) and funded by the Swedish Research Council (VR), the member universities (KTH, UU, KI, SU), SciLifeLab, and external grants, and operate according to the guidelines of the VR Council for Research Infrastructures (VR-RFI).

In this proposal NGI applies for funds to further develop its genomics services by expanding its technology repertoire to include the MGI sequencing technology (the DNBSEQ-T7 instrument).

MGI is the only new technology on the commercial market that can challenge existing short-read sequencing approaches in terms of price and throughput, and the investment would ensure that NGI stays at the forefront of genome technology.

As genome sequencing and genotyping analyses represent a cornerstone of biology and medicine, with a very wide range of applications, such equipment upgrades will ensure that NGI will continue to play a central role in providing cutting-edge technologies, enabling Swedish research groups to perform world-class research projects.