Sonophoresis smartpatch for pain-free, controllable, and wearable transdermal drug delivery

Wearable SmartPatch is a unique needle-free drug delivery solution, based on a patented electronic system, that opens skin pores temporarily to deliver macromolecular drugs.

It generates sound waves (Sonophoresis) that increase the size of the skin pores without pain or damage and passes drugs like insulin, heparin, or EPO (>50KDa) through, reaching the hypodermis and capillary vessels, without altering the pharmacokinetic profile of the drug.It has a durable part with 3-year warranty including the ultrasound generator, electronics, and battery, and a disposable and recyclable piece that encloses the adhesive and the drug reservoir with up to 2mL (average for 3 days of treatment), changeable in less than 2 minutes.The device can vary both the absorption rate and the depth reached depending on programmed stimulation parameters, which allows adaptation to different skin types and therapeutic uses.

Our tests have shown absorption rates of at least 0,05 mL/minute on a 1 cm2 pig skin area