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Active HORIZON European Commission

A novel combination treatment effective against all multidrug-resistant pathogens deemed as a critical priority by the WHO

€23.98M EUR

Funder European Commission
Recipient Organization Antabio
Country France
Start Date Feb 01, 2023
End Date Apr 30, 2026
Duration 1,184 days
Number of Grantees 1
Roles Coordinator
Data Source European Commission
Grant ID 190159682
Grant Description

Antimicrobial resistance (AMR) due to multidrug-resistant Gram-negative bacteria are an increasingly serious healthcare threat, exacerbated by major economic issues underlying the development of new antibacterial drugs.

The effectiveness of -lactam antibiotics, the most important class of antibacterial agents, is impaired by the production of -lactamase enzymes by drug-resistant bacteria.

We are developing a combination of a well-known antibiotic (meropenem) and ANT3310, our proprietary, best-in-class serine--lactamase inhibitor, intended for the treatment of hospital-acquired infections caused by drug-resistant pathogens.

Our treatment has been pre-clinically proven to be efficacious against all three pathogens deemed a critical priority by the World Health Organization (WHO).We will conduct three clinical trials and next out-license ANT3310 to a pharmaceutical partner. We expect market approval by 2029 and that ANT3310 will generate over 10bn in sales within 13-years.

All Grantees

Antabio

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