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Completed HORIZON European Commission

Breakthrough Brain Stimulation Device for Epilepsy

€3.57M EUR

Funder European Commission
Recipient Organization Precisis Gmbh
Country Germany
Start Date Mar 01, 2023
End Date Feb 28, 2025
Duration 730 days
Number of Grantees 1
Roles Coordinator
Data Source European Commission
Grant ID 190133715
Grant Description

EASEE stands for epicranial application of stimulation electrodes in epilepsy. It is the first minimally invasive device for focal cortical stimulation.

Based on the Laplace electrode (central electrode surrounded by a ring electrode), EASEE features 4 distinct electrodes replacing the outer ring, connected to 4 independent current sources to account for impedance and anatomical variances in the human skull. Still, the characteristic quadrupolar local electric field with high penetration depth is maintained.

The stimulation pattern is one of a kind. EASEE is equipped for high frequency, DC-like, and low-frequency stimulation, depending on the condition to be treated.

In epilepsy, intermittent high-frequency stimulation bursts throughout the day are combined with a 20min DC-like stimulation session.

This first is meant to terminate upcoming seizures, the second to initiate neuromodulatory processes to down-regulate the overexcitability of the epileptic brain area.

All Grantees

Precisis Gmbh

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