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| Funder | NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES |
|---|---|
| Recipient Organization | Duke University |
| Country | United States |
| Start Date | Sep 01, 2024 |
| End Date | Aug 31, 2026 |
| Duration | 729 days |
| Number of Grantees | 3 |
| Roles | Co-Investigator; Principal Investigator |
| Data Source | NIH (US) |
| Grant ID | 11100982 |
Laser lithotripsy (LL) is commonly used for kidney stone treatment, with cavitation playing a crucial role in stone
fragmentation. However, the relationship between cavitation activities and stone damage remains unclear. This supplement study by Anthony DiSpirito will utilize deep learning to predict stone damage based on passive cavitation mapping (PCM) signals. A three-dimensional PCM system will be employed, along with B-mode Ultrasound (US) for data acquisition. Deep
learning enables the optimization of LL procedures by automating feature selection and identifying key factors driving stone
damage. Our approach will offer valuable insights into medical practice, advancing the efficacy of LL treatments. We will
adopt deep learning module combined with cavitation activities information, and we can better predict the potential damaged
induced by bubble collapsing. Our result will also demonstrate the strong correlation between bubble collapsing information with stone crater damage. This approach can also be further explored with more sophisticated scenarios and clinical applications.
Duke University
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