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Active NON-SBIR/STTR RPGS NIH (US)

Reducing anemia among young, preconception women in Nepal through a household level group norm and behavior change intervention and micronutrient supplementation

$6.03M USD

Funder EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT
Recipient Organization University of California, San Francisco
Country United States
Start Date Sep 01, 2024
End Date May 31, 2029
Duration 1,733 days
Number of Grantees 1
Roles Principal Investigator
Data Source NIH (US)
Grant ID 10993336
Grant Description

ABSRACT Preconception micronutrient status (including anemia) is a critical determinant of maternal, newborn, and child health that remains undervalued in Nepal. However, providing micronutrient supplements (MMS) alone is not enough. In the Nepali context, the gap between marriage and the first birth is short and newly married

women have the lowest household status. Addressing the intersectional barriers to health for newly married women, including inequitable gender norms and women’s empowerment, household relationships, nutrition knowledge and practices—is essential for improving maternal and infant outcomes in Nepal. To mitigate the

community, household, and individual factors resulting in poor nutrition, our team developed and pilot-tested an educational group intervention (Sumadhur, meaning “Best Relationship”) for newly married women, husbands, and mothers-in-law triads. Sumadhur aims to provide information on nutrition and women’s health, address

inequitable gender norms and practices, strengthen household relationships and communication, and improve the household status of newly married women. The pilot study of Sumadhur brought triads of several households together for 16 interrelated sessions over four-months. Findings suggest that participants (N=90)

found the intervention to be highly feasible and acceptable and nutritional norms and practices improved. We propose to test the effectiveness of Sumadhur on maternal health and nutrition outcomes using a 2-arm cluster RCT (cRCT). The intervention participants will receive the Sumadhur group intervention and will be

provided MMS directly at group sessions. In control villages who do not receive the Sumadhur group intervention, we will facilitate access to MMS at primary health centers. We will randomize 70 villages to each arm (with one group per village). Each village has one group of five women (total of 700 women). Newly married women, their

husbands and mothers-in-laws (total=2,100), will be followed four times for 18 months post-intervention through surveys, hemoglobin tests and blood draws (women only). Our specific aims are to estimate the effectiveness of Sumadhur on women’s anemia and micronutrient status, including the cost-benefit of the intervention (Aim 1);

explore the impact on intermediate outcomes such as gender norms, household relationships and eating practices and characterize the individual and household-level mechanisms of impact (Aim 2); understand triadic experiences and impact over time of Sumadhur (Aim 3). Accomplishing these aims will provide evidence for how to improve micronutrient and anemia status among

women before they become pregnant—thereby ensuring that women are not deficient in the critical early phases of pregnancy. These findings will also advance the field by testing novel approaches (household and community level behavior and norm change intervention) that, when combined with supplements, may lead to

better adherence, uptake, and, ultimately, health outcomes, and have additional longer-term benefits.

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University of California, San Francisco

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