Using artificial intelligence to bridge human and murine studies of lupus nephritis progression

$7.53M USD

Funder	NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
Recipient Organization	University of Chicago
Country	United States
Start Date	Aug 15, 2024
End Date	Jul 31, 2029
Duration	1,811 days
Number of Grantees	3
Roles	Principal Investigator; Co-Investigator
Data Source	NIH (US)
Grant ID	`10981178`

Grant Description

PROJECT SUMMARY Lupus nephritis (LN) is the most common severe manifestation of systemic lupus erythematosus (SLE) Disease progression is associated with tubulointerstitial hypoxia and metabolic dysfunction, capillary rarefaction, accumulation of immune infiltrates and fibrosis. Complete remission rates in patients with LN are