Wake Forest University Vesicant Exposure Resource and Coordination Core

Project Summary – Administrative Core Successful execution of the Vesicant ExRC relies on the establishment of a strong Administrative Core (AC) to oversee and coordinate all operations. By leveraging the administrative expertise and resources of the Wake Forest Institute for Regenerative Medicine (WFIRM), where most Vesicant ExRC operations will be co-located,

the AC will ensure bi-directional exchange and synergism among Facility Cores, NIH program managers, and CCRP collaborators. The AC will be organized using program management principles developed by WFIRM staff while managing more than $300M in large, multi-institution programs over the last decade. The AC will be

led by the Vesicant ExRC Director, who will be assisted by an Administrative Program Manager and a seasoned administrative team already located within WFIRM. The AC will support management and research coordination of the Vesicant ExRC via five specific aims: 1) establish business practices to guide Vesicant ExRC

programmatic and operational decisions; 2) facilitate communication among the Vesicant ExRC and NIH leadership, CCRP-funded investigators, other ExRC facilities and stakeholders; 3) refine operating procedures based on quality control and participant feedback; 4) establish training resources to educate the CCRP

community; and 5) develop an evidence-based transition plan to sustain CCRP function as an independent facility. The Vesicant ExRC will be guided by a seasoned administrative team with proven expertise in managing large, multi-institution programs involving academic and corporate participants. The implementation of proven

business practices throughout the Vesicant ExRC will support the CCRP community by accelerating exposure operations, facilitating open and transparent practices, and establishing a sound foundation for conducting rigorous and efficient Vesicant ExRC operations and transitioning to a self-sustaining resource after NIH support

is complete.