Southern California Center for Chronic Health Disparities in Latino Children and Families.

Project Summary/Abstract The prevalence of prediabetes and type 2 diabetes (T2D) among Latino adults in the United States is a significant health concern. With T2D affecting approximately 15% of Latinos, accounting for about 10 million individuals, there is a clear disparity compared to non-Hispanic Whites. The overarching goal of this innovative

intervention project is to enhance glycemic control in individuals with prediabetes and prevent the progression to T2D among Latinos. This project aims to develop and evaluate a new intervention, called Mi Control!, which combines continuous glucose monitoring (CGM) feedback using the latest non-invasive self-monitoring

technology with T2D prevention educational video clips. The intervention will specifically target the needs of Latinos, based on information gathered from the experiences and feedback of Spanish- and/or English- speaking Latino community health workers (Promotores) wearing CGM devices. The project consists of three

iterative studies to achieve its objectives: Study 1: This intervention development study will involve 20 Promotores de salud, who will wear a CGM sensor for 14 days. The sensor will provide real-time smartphone visual and audio feedback on glycemic variability, and participants will maintain timestamped dietary records.

Video-recorded interviews will be conducted to capture the experiential narrative and explore the benefits, barriers, and behavior changes related to the CGM device. Video clips will be selected and edited from these interviews to create a series of smartphone-based educational clips for the intervention. An artificial intelligence

(AI) tool will be utilized for language translation. Study 2: This feasibility study aims to assess the impact of Mi Control! on glycemic data capture and outcomes among an independent sample of 30 Promotores with prediabetes. Participants will wear the CGM device for 14 days, and the study will include a control period

followed by a period with unmasked CGM glycemic feedback and smartphone text links to the Mi Control! video clips. Measures of satisfaction with the CGM device and the intervention will be collected. The study will evaluate the feasibility of Mi Control! augmented by the AI tool for language translation, and its impact on

glycemic control and knowledge retention among the Latino Promotores with confirmed prediabetes. Study 3: This generality study aims to assess the effectiveness of Mi Control! on glycemic control and dietary behavior among a community-based sample of 40 Latino parents with confirmed prediabetes. Participants will be

parents of children recruited from an ongoing cohort study of Latino families (Center Project 1). Participants will experience the same study method as in Study 2 and glycemic control and dietary behavior during the masked and unmasked phases will be compared. Overall, this project will contribute to the development of an

innovative intervention to improve prediabetes glycemic control and prevent T2D in the Latino population. By utilizing emerging technologies, such as CGM and AI, and tailoring the intervention to the specific needs of Latinos, this research aims to address the significant health disparities observed in this population.