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| Funder | NATIONAL CENTER FOR COMPLEMENTARY & INTEGRATIVE HEALTH |
|---|---|
| Recipient Organization | University of California, San Francisco |
| Country | United States |
| Start Date | Aug 01, 2024 |
| End Date | Jul 31, 2029 |
| Duration | 1,825 days |
| Number of Grantees | 2 |
| Roles | Co-Investigator; Principal Investigator |
| Data Source | NIH (US) |
| Grant ID | 10881523 |
PROJECT SUMMARY One out of seven women suffer from chronic pelvic pain, a syndrome leading to depression, social isolation, sexual dysfunction, physical inactivity, and progressive pain-related disability. Unfortunately, few clinical treatments for chronic pelvic pain are supported by rigorous evidence of efficacy, and most have limitations
that decrease their safety or accessibility for many women in the community. Women with chronic pelvic pain also have high rates of exposure to sexual and interpersonal trauma, which can complicate their engagement with clinical treatments. As a result, many women are anxious to identify alternate management strategies for
pelvic pain that are not only effective but better tolerated, more patient-centered, and more accessible. Yoga is a set of complementary physical and mental practices with the potential to improve pelvic pain in women through multiple mechanisms. When practiced in a way that emphasizes careful practice of yoga
postures, mindful awareness of body structures (such as the pelvic floor), deep breathing and relaxation techniques, and trauma-informed care principles, yoga can be used to help women improve pelvic floor dysfunction, correct maladaptive postural and physical behaviors, decrease comorbid anxiety and perceived
stress, and overcome deconditioning associated with chronic pain. Furthermore, yoga as a complementary treatment modality does not require intensive supervision by clinician specialists or repeated visits to healthcare facilities. With the rise of videoconference-based yoga instruction, women do not even need to
travel back and forth to brick-and mortar yoga studios, but instead gain access to specialized yoga instruction, maintain regular yoga practice, and interact with others with the same indication from their own homes. To evaluate the feasibility of pelvic yoga as a complementary management strategy for women with chronic
pelvic pain, our team collaborated with an expert yoga panel to develop and refine a structured pelvic yoga program grounded in a biophysiological model of female chronic pelvic pain. In a randomized feasibility trial, women with chronic pelvic pain recruited from multiple locations in California were randomly assigned to a
study yoga program consisting of twice-weekly group classes conducted by videoconference supplemented by once weekly individual practice, or a control program of time-equivalent group instruction and individual practice of non-specific muscle stretching and strengthening exercises. Following the successful completion of
this pilot, we now propose to conduct a full-scale, fully remote trial in women recruited nationally, to rigorously evaluate the efficacy of remotely delivered pelvic yoga and to explore potential mediators of treatment benefit. This research is designed to provide rigorous evidence of the efficacy and safety of a remotely delivered pelvic
yoga program as a potentially patient-centered, scalable, community-based self-management strategy for chronic pelvic pain, as one of the most burdensome, complex, and common pain syndromes in women.
University of California, San Francisco
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