Research Bronchoscopy and Biospecimens Core

PROJECT SUMMARY/ABSTRACT Core B: Bronchoscopy and Biospecimens The goal of this core is four-fold. First, the core is responsible for performing bronchoscopy on study subjects to obtain all the necessary lung specimens for in vitro experiments. This includes collecting all the appropriate control specimens at the time of study. Second, the core is responsible for processing

specimens in such a way that they can either be used real time or stored appropriately for future use. This includes coordination of processing and storage protocols between labs. Third, the core is responsible for aliquoting samples in appropriate sizes and conditions (i.e. RNA preservation media, DMSO) for storage in

appropriate environments (i.e. -80o freezer, liquid nitrogen) for future studies. Finally, the core is responsible for labeling and tracking all specimens, including the linkage of specimens to subject metadata. By providing uniform specimens to all investigators the core can ensure interdisciplinary integration of the multiple projects

that make up the combined Program Project.