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| Funder | NATIONAL INSTITUTE ON DRUG ABUSE |
|---|---|
| Recipient Organization | Brown University |
| Country | United States |
| Start Date | Jul 15, 2022 |
| End Date | Apr 30, 2027 |
| Duration | 1,750 days |
| Number of Grantees | 2 |
| Roles | Co-Investigator; Principal Investigator |
| Data Source | NIH (US) |
| Grant ID | 10814840 |
With the majority of US states having adopted legislation to medically and/or recreationally legalize cannabis, public perception of the drug is now overwhelmingly favorable. Increased access and prevalence of use are accompanied by perceptions of low health risk and/or of therapeutic benefits associated with cannabis use.
Aside from evidence for symptom relief in certain medical conditions, evidence regarding therapeutic effects of cannabis for many conditions remains elusive, leaving the decision regarding when and how to use cannabis to the user. Both therapeutic and recreational reasons (motives) for CU are largely shaped through exposure to
messages about the effects of cannabis, yet little is known about the source of messaging, how it is transmitted to users, how it shapes their thinking, and ultimately its association with CU patterns. The proposed study will gather critical information about message sources, cannabis-promoting content, and risk warnings being
disseminated to cannabis users as well as the messages being received, their effects on CU motives, and subsequent CU. The mixed-methods design will include two phases. Phase 1 involves semi-structured interviews conducted with 1) cannabis users, as well as with message sources, including 2) cannabis
dispensary and retail outlet staff (budtenders), 3) growers, and 4) health care providers who discuss cannabis with patients. Additionally, extraction and coding of messaging content will be conducted across internet and social media messaging platforms. Observational coding of recreational/medical cannabis outlets will be
conducted using validated surveillance tools. Together, these data permit characterization of cannabis messaging content across various types of sources and platforms (Aim 1) that will in turn inform Phase 2 methods. Phase 2 consists of a three-burst 4-week ecological momentary assessment (EMA) study with a
sample (N=300) of weekly 18-74-year-old cannabis users. Participants will complete brief smartphone-based measures of exposure to messaging (source and content), cannabis motives, and use patterns in the natural environment. With these quantitative data, this will be the first study to examine prospective associations
between a user’s exposure to cannabis messaging and motives and other cognitions (Aim 2). Further, we will test whether cannabis motives are a mechanism underlying the association between cannabis messaging and CU at both the between-person and within-person levels (Aim 3). Finally, we will explore user characteristics
and message source characteristics as potential moderators of the effects of cannabis messaging and CU (Aim 4). This combination of complementary and highly rigorous data collection approaches will provide the most nuanced understanding of the messages being disseminated about the effects of cannabis to the
cannabis user. Findings will arm policy makers and cannabis regulatory science with evidence-based information about the impact of cannabis messaging that can ultimately reduce potential harms from misuse.
Brown University
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