A soft magnetoelastic microneedle patch for rapid skin cancer screening

$3.51M USD

Funder	NATIONAL CANCER INSTITUTE
Recipient Organization	University of California Los Angeles
Country	United States
Start Date	Apr 01, 2024
End Date	Mar 31, 2029
Duration	1,825 days
Number of Grantees	1
Roles	Principal Investigator
Data Source	NIH (US)
Grant ID	`10781736`

Grant Description

PROJECT SUMMARY Over 2.5 million skin cancers are diagnosed annually in the United States, more than all other forms of cancers combined. Early diagnosis is critical; thus, we propose to develop a soft and wearable magnetoelastic microneedle patch (MMP) for non-invasive and rapid skin cancer screening. It could perform fast scanning of the

spatial stiffness of skin lesions with depths of up to 5 mm. This concept is established on the basis of the PI’s prior success in discovering the giant magnetoelastic effect in soft matter (Nat. Mater. 2021, 20, 1670). With a fundamentally new working mechanism, the proposed soft MMP can cover a large detection area (7.7 cm2) and

have a high spatial resolution (1 mm, trained with super-resolution algorithm), high framerate (2000 Hz), and ultrahigh sensitivity (