Biostatistics Core

CORE C: Biostatistics/Bioinformatics Core PROJECT SUMMARY/ABSTRACT The Biostatistics and Bioinformatics Core (Core C) provides support to the 3 primary projects, and Career Enhancement and Developmental Research projects of the Prostate Cancer SPORE in the areas of study design, data collection and visualization, database development and management, data quality control, data

analysis, clinical trial monitoring, bioinformatics, and interpretation. In this regard, members of the Core play an integral role as members of the team for each project, and provide solutions to commonplace and complex or unique problems that arise during the planning and execution of the projects. Each project has a primary

biostatistician/epidemiologist thoroughly versed in the subject matter associated with the project. Core members also interact on a regular basis, and work closely with the Administrative (Core A) and Pathology (Core B) Cores, which contributes to interactions and synergy among the projects. Core investigators have

extensive experience in a wide range of biostatistical, bioinformatics, epidemiologic and translational research methodologies and applications, and have also developed novel methods, some of which will be used in this SPORE. Because of the emphasis on translational science in the SPORE program, the Core also includes

members with experience in both epidemiology and biostatistics, who provide important input for translating basic science to clinical trials and population cohorts.