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Active NON-SBIR/STTR RPGS NIH (US)

The Impact of Biologic Aging on Immunity-Related Cervical Cancer Outcome Disparities Among Women Living with HIV in Zambia

$6.66M USD

Funder NATIONAL CANCER INSTITUTE
Recipient Organization University of Tx Md Anderson Can Ctr
Country United States
Start Date Sep 19, 2023
End Date Aug 31, 2028
Duration 1,808 days
Number of Grantees 3
Roles Co-Investigator; Principal Investigator
Data Source NIH (US)
Grant ID 10754783
Grant Description

Project Summary/Abstract Cervical cancer disproportionately affects women of color from low-socioeconomic geographical locations. Locations, such as sub-Saharan Africa, can also have a high incidence of Human Immunodeficiency Virus (HIV) infection, and access to cervical cancer screening is generally limited for women living in these underserved

communities. Furthermore, People Living with Human Immunodeficiency Virus (PLWH) have evidence of premature aging, which could contribute to cervical cancer progression and responses to chemoradiation therapy (CRT). CRT is the standard of care for locally advanced cervical cancer, and older women (≥52-years of age)

treated with CRT have worse side effects than younger (

All Grantees

University of Tx Md Anderson Can Ctr

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