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Active NON-SBIR/STTR RPGS NIH (US)

Assessing the Efficacy of an Acceptance-Based Digital Intervention to Improve Functioning for Veterans with Chronic Pain


Funder Veterans Affairs
Recipient Organization Edith Nourse Rogers Memorial Veterans Hospital
Country United States
Start Date Nov 01, 2023
End Date Oct 31, 2027
Duration 1,460 days
Number of Grantees 1
Roles Principal Investigator
Data Source NIH (US)
Grant ID 10752825
Grant Description

Chronic pain (CP) is a serious concern that disproportionately affects Veterans compared to the general public; Veterans are diagnosed with CP at high rates (47 – 56%) with a 40% greater rate of severe pain than non-Veterans. The negative functional outcomes of chronic pain among Veterans are wide-ranging and include

decreased ability to complete daily work activities, less social support from and closeness with family members, increased chronic health conditions (e.g., heart disease), and higher mortality compared to Veterans without chronic pain. Unfortunately, the use of medication for long-term pain treatment, though often utilized, has

both limited efficacy and potentially harmful outcomes. Given these concerns, there is an urgent need for innovative and integrative approaches for non-medical pain self-management. Despite the critical importance of effective pain self-management programs, many Veterans with chronic pain do not engage in the pain self-

management programs currently offered by VA. There are numerous reasons for this, including perceived time and transportation concerns and pain-related barriers to attending in-person care. Thus, the development and evaluation of innovative, evidence-based interventions for pain management that can be accessed from home is

a crucial step towards improving quality of life for Veterans with chronic pain. One approach with over twenty years of efficacious treatment for chronic pain is Acceptance and Commitment Therapy for Chronic Pain (ACT-CP). ACT is a well-established and VA-approved approach to chronic pain management, and focuses on committing to behavior change that reflects personal values, leading

to significant improvement in life functioning. Though provided at many VA hospitals, clinician-delivered ACT for chronic pain has not had a nationwide rollout and is not available at all VA pain clinics. Additionally, many Veterans with chronic pain do not access one-on-one therapeutic treatment due to transportation and time

issues. Thankfully, for adults with chronic pain outside of the VA, technology-delivered ACT has been found to be acceptable, useful, and efficacious in delivering pain treatment. However, although research suggests it could help with at-home pain management, no ACT for chronic pain online treatment exists specifically for

Veterans and their particular care needs. To address this treatment option gap, our research team created an online Veteran ACT for chronic pain (VACT-CP) during the PI’s Rehabilitation R&D CDA-2 project. VACT-CP is guided by an interactive virtual coach (Coach Anne) to help address pain-related distress and functional difficulties of chronic pain (e.g.,

avoidance, reactivity) over seven weeks of treatment. Preliminary findings demonstrate that VACT-CP is highly usable, perceived as helpful, and can help Veterans increase their pain acceptance and pain management. The primary outcomes for this project will be to complete a three-site, fully-powered efficacy trial comparing VACT-

CP to an active online control condition (total n = 200) to investigate whether VACT-CP can improve pain- related functioning and quality of life. In addition, we will analyze data from the VACT-CP group to assess whether the hypothesized mechanism of change (psychological flexibility) mediates the impact of pain severity

on pain-related functioning.

All Grantees

Edith Nourse Rogers Memorial Veterans Hospital

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