2023 Drug Metabolism Gordon Research Conference and Gordon Research Seminar

Abstract The field of Drug Metabolism is focused on defining and mechanistically understanding the Absorption, Distribution, Metabolism and Elimination (ADME) properties of a molecule. ADME has a tremendous influence on efficacy, safety, and dosing of therapeutic molecules and novel modalities, beyond small

and large molecules, are amongst the medicines of today and tomorrow. The 51st Drug Metabolism GRC will focus on the challenges and opportunities of the next 50-years of ADME science. Emphasis will be on cutting-edge science and the importance of interconnectedness among ADME disciplines so that we fully tap into the potential of emerging technologies and novel approaches in discovering,

developing, and safely using medicine from diverse modalities. The conference will bring together academic, industry and regulatory scientists at all career stages and provide a stimulating and collaborative environment to discuss unpublished research and learn about the ADME challenges of diverse modalities. The informal venue of the Drug Metabolism GRC provides an ideal environment to

establish this. This conference will provide a forum for early career scientists to expand their scientific breadth, interact with leaders in the field, establish future collaborative relationships, and consider various career paths. A Gordon Research Seminar will precede the main GRC conference, providing a

unique environment for students and early career researchers to present their work, connect and have access to mentoring. Attendees will be exposed to cutting edge presentations by world-class speakers to stimulate new ideas and collaborations with focus on diversity and connectivity driving translational

ADME science so that new treatments and cures can be delivered to patients faster. The lectures are held in the mornings and evenings over 4.5 days with the afternoons available for informal discussions and recreation. GRC meetings are small and designed for more discussion time during both the formal

scientific sessions and during informal interactions (e.g., poster sessions, mealtimes, afternoon outings). To facilitate ample opportunity to discuss their work, the Drug Metabolism GRC organizes four, two-hour poster sessions, with each poster presenter (at least 60) available for discussion during two sessions.