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Completed NON-SBIR/STTR RPGS NIH (US)

Development of a Novel Virtual Reality Treatment for Emerging Adults with ADHD

$5.99M USD

Funder NATIONAL INSTITUTE OF MENTAL HEALTH
Recipient Organization Rutgers, the State University of N.J.
Country United States
Start Date Aug 01, 2023
End Date Jul 31, 2025
Duration 730 days
Number of Grantees 2
Roles Principal Investigator; Co-Investigator
Data Source NIH (US)
Grant ID 10721084
Grant Description

Project Summary/Abstract Attention deficit hyperactivity disorder (ADHD) is a highly prevalent and impairing disorder. Behavioral treatments that structure the environment and provide frequent and consistent monitoring are efficacious but resource and time intensive, leading to problems with access and adherence. This study will utilize a virtual

reality platform to minimize distractions and provide the structure and monitoring necessary for individuals with ADHD to maintain focus while completing homework and studying. The virtual reality (VR) headset will place students in a distraction free environment that automates the frequent and consistent point-of-performance

feedback and reinforcement that serves as the core mechanisms of behavioral treatment. The VR technology will allow for direct comparison between two novel intervention approaches and a VR passthrough to laptop control. Survey and objective data (keyboard and mouse click data) will be collected to directly evaluate the

impact of VR on core targets of action, including concentration, motivation, and homework effort. This novel alternative to medication and behavior therapy offers a completely new tool for supporting individuals with ADHD. This study includes four separate projects, three in the R61 phase and a large randomized trial in the

R33 phase. Project 1 (N = 30 college students with ADHD) focuses on optimizing and refining objective data capture algorithms to quantify on-task behavior and work productivity while completing a variety of different types of academic tasks. Project 2 (N = 30 college students with ADHD) focuses on developing and refining

on-task monitoring and performance feedback algorithms within VR, including a green, yellow, and red-light display that allows individuals with ADHD to receive consistent and frequent feedback and work towards specific short-terms goals and rewards. Focus groups will also be completed to improve VR feasibility and

usability. Project 3 involves a small randomized controlled trial to ensure that the key targets of action are engaged. Project 3 will assess the feasibility/usability and preliminary effects of the VR environment alone (n=15) as compared to VR environment + contingency management (n=15) and a passthrough control wearing

of the VR headset (n=15). Time on-task, homework motivation, and homework effort are the proposed mechanisms of action. If the Go/No-Go criteria are met in Project 3, the protocol moves to Project 4, which involves a randomized trial of the VR intervention. 252 college students with ADHD will be randomized to

receive either: (1) VR environment alone, (2) VR environment + contingency management, or (3) pass-through VR headset control for 8 weeks. Measures of mental health and academic functioning will be collected at baseline, 4 weeks, 8 weeks, and at a 3-month follow-up.

All Grantees

Rutgers, the State University of N.J.

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