ELABORATION AND USE OF SYNGENIC PRE-CLINICAL MODELS FOR CANCER DRUG DEVELOPMENT

$121.49M USD

Funder	NATIONAL CANCER INSTITUTE
Recipient Organization	Leidos Biomedical Research, Inc.
Country	United States
Start Date	Sep 16, 2021
End Date	Sep 15, 2026
Duration	1,825 days
Number of Grantees	1
Roles	Principal Investigator
Data Source	NIH (US)
Grant ID	`10502661`

Grant Description

The Division of Cancer Treatment and Diagnosis, NCI is requesting support for the development and/or use of existing syngeneic model systems for the pre-clinical evaluation and testing of anti-cancer agents in the presence of an intact immune system.

This is of particular interest for immuno-oncology (I/O) agents which cannot be evaluated in the standard xenograft model systems requiring the use of immunocompromised animals.