Role of ILC2 and eosinophils in abdominal aortic aneurysm

$6.8M USD

Funder	NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
Recipient Organization	Brigham and Women'S Hospital
Country	United States
Start Date	Jan 01, 2021
End Date	Dec 31, 2024
Duration	1,460 days
Number of Grantees	1
Roles	Principal Investigator
Data Source	NIH (US)
Grant ID	`10322053`

Grant Description

Abdominal aortic aneurysm (AAA) affects 0.5~3.2% of the general populations in US and worldwide. Besides adjusting lifestyle, open surgery and endovascular stent grafting remain the main treatments, though attempts have been made to develop non-invasive medications. Group 2 innate lymphoid cells (ILC2) are innate

lymphocytes that play essential role in obesity, although their total numbers are nearly undetectable (