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Completed GRANT FOR R&D UKRI Gateway to Research

Phax: A Rapid Cell-Free Phage Discovery Platform for Scalable Personalised Antimicrobial Therapies

£499.4K GBP

Funder TMF
Recipient Organization Katana Bioworks Ltd
Country United Kingdom
Start Date Dec 01, 2024
End Date Mar 30, 2025
Duration 119 days
Data Source UKRI Gateway to Research
Grant ID 10139599
Grant Description

Phage therapy is an essential strategy to mitigate the impact of antibiotic-resistance, and the Katana Bioworks Phax platform will enable scalable phage therapy by reducing costs and lead-time.

While phage therapy is safe and effective, broad adoption/application is limited by the lead-time to identify then manufacture phage (median 171 days).

Phax is a rapid lead-to-hit phage discovery workflow pairing _in silico_ phage prediction and cell-free bacteriophage synthesis (CFBS) to engineer personalised phage therapy on-demand.

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