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Active HORIZON European Commission

deepHelix: a massively scalable, AI-powered peptide drug discovery platform


Funder European Commission
Recipient Organization Fundacio Centre de Regulacio Genomica
Country Spain
Start Date Mar 01, 2025
End Date Aug 31, 2026
Duration 548 days
Number of Grantees 1
Roles Coordinator
Data Source European Commission
Grant ID 101213167
Grant Description

Peptide drugs potentially address limitations of both small molecules and antibodies.

Small molecules struggle to target protein-protein interactions (PPIs), while antibodies cannot access intracellular proteins.

In this project we will develop an AI-driven experimental platform to produce cell-permeable therapeutic peptides made entirely of natural amino acids.

The platform will allow the rapid discovery of cost-effective, stable, cell-permeable, and high-affinity peptide binders for use as research tools, in diagnostics, and as therapeutics against intracellular proteins previously considered undruggable targets.

All Grantees

Fundacio Centre de Regulacio Genomica

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