Development of a Sustainable, Low-cost and Long-term Lab-on-a-Chip colorimetric paper-based sensor for saxotoxin quantification in water and seafood

Dr.

Sara Santiago Malagón will conduct a fellowship focused on developing a Lab-on-a-Chip (LOC) colorimetric paper-based device for point-of-need (PON) detection of saxitoxin, a toxin produced by cyanobacteria and certain microalgae.

The primary objective of this project is to mitigate cyanobacteria contamination in stagnant water and harmful algae bloom (HAB) occurrences in seawater, which can lead to the death of marine species and the poisoning of animals and humans.

We aim to validate an accessible, eco-friendly, cost-effective, and user-friendly technology that can be extended to detect and quantify various biotoxins relevant to public health and the environment.

The driving force behind this project is the current gap in the development of portable sensor systems for environmental applications in marine ecosystems, freshwater, and seafood quality control, all without the need for specialized equipment.In addition to the research that will help control and prevent damage to the ecosystem and preserve species diversity, the methodology and materials presented are sustainable and environmentally friendly, aligning with the project's environmental commitment.

Furthermore, the materials used (silk) will facilitate the stabilization of biomacromolecules required for the detection and quantification of saxitoxin, enabling the creation of long-span sensors.

Ultimately, the end goal is to validate that the colorimetric device, designed as a toolless system, can be operated by minimally trained volunteers (end users) through a user-friendly mobile application interface, even if they do not possess specialized knowledge or skills.

These individuals play a crucial role in environmental preservation and prevention efforts.This grant would offer the applicant the opportunity to lead an international project, fostering collaborations with esteemed institutions and researchers for future global initiatives.