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Unspecific Peroxygenases for the Oxidation of Arenes
| Funder | European Commission |
|---|---|
| Recipient Organization | Technische Universiteit Delft |
| Country | Netherlands |
| Start Date | Nov 01, 2024 |
| End Date | Oct 31, 2026 |
| Duration | 729 days |
| Number of Grantees | 2 |
| Roles | Associated Partner; Coordinator |
| Data Source | European Commission |
| Grant ID | 101151329 |
Grant Description
UPOXARENE is an interdisciplinary project combining organic synthesis, biocatalysis, and protein engineering, to realise the elusive epoxidation of arenes in a single step using engineered unspecific peroxygenases (UPOs).
The compatibility of UPOs with organic media will be exploited to expand their chemistry beyond the aromatic hydroxylation accessible with cytochrome P450s.
The utility of the method will be demonstrated through the preparation of industrially relevant products in continuous chemo-enzymatic cascades, in alignment with the principles set out in the MSCA Green Charter.
UPOXARENE will promote biotechnology through the citizen-science initiative Peroxynauts, encouraging students from all backgrounds to pursue careers in the life sciences.
All Grantees
Icp -Instituto de Catálisis Y Petroleoquímica; Technische Universiteit Delft
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