SWEEPICS: SWEPT LASERS FOR NON-INVASIVE DIAGNOSTICS

Swept lasers have enabled paradigm-shifts in biomedical imaging and diagnostics.

The SWEEPICS project will research and develop the next generation of swept source lasers with flexible pulse modulation capability, high power output, multi-wavelength coherent output and multi-application potential.

SWEEPICS will develop new laser-based systems: a high-speed, high resolution multiphoton high content screening system, a multimodal non-invasive imaging system based on high-speed photoacoustics and multiphoton microscopy, and a smart microscope for accelerated acquisition&diagnostics.

The inter-disciplinary consortium of European partners will showcase the SWEEPICS technology in cutting-edge use cases based on novel vascular organoids for animal-free drug-testing and infection studies.

This disruptive SWEEPICS technology will rapidly generate high-resolution diagnostic imaging in three-dimension, where the high imaging depth permits penetrating millimeter deep into tissue-like organoids and imaging at high temporal and spatial resolution in order to allow for a drastic reduction of animal testing and increased speed of diagnostic results.

It will allow the study of dynamic processes in real-time and at multiple length scales, enabling researchers to observe how cells and tissues respond to viral infections or pathogen-induced inflammation, while also permitting a high-throughput enabled discovery of novel diagnostic biomarkers.Overall, this technology represents a major breakthrough in capable laser technology for high accuracy and throughput medical diagnostics and is poised to make significant contributions to the European laser and biomedical technology landscape.